François-Hugues Porée, Assistant Professor (MC-HDR)

 Vitae______________________________________________

 2012. HDR (habilitation). Université Paris Descartes

2005. Assistant Professor (Laboratoire de Pharmacognosie UMR CNRS 8638, Faculté de Pharmacie de Paris - Université Paris Descartes

2003-2004. Postdoctoral fellow at the Max Planck Institut für Kohlenforschung (Pr Fürstner)

2003. PhD in Organic Chemistry at Université de Cergy-Pontoise (Dr Pancrazi and Pr Ardisson) (Dina Surdin Award from the French Chemical Society)

2001. PhD in Pharmacy. Faculté de Pharmacie de Châtenay-Malabry, Université Paris Sud

2000. Master Degree in Organic Chemistry (Ecole Polytechnique, Palaiseau, France)

1976. Born in Paris (France)

 

Research_____________________________________________

Keywords. Alkaloids, total synthesis, catalysis, chirality, mushrooms,

Theme 1. Synthetic tools for Natural Product Chemistry : developments on the hetero Pauson Khand reaction to access Securinega alkaloids series (see Publication 19).

 

Theme 2. Phytochemical investigations. (1) Phytochemical studies on plants belonging to the Phyllanthaceae family (see publication 18). (2) Connecting genetics to secondary metabolites: phytochemical studies on selected filamentous fungi (collaboration with Dr F Leclerc, G Ruprich-Robert and H Lalucque, Université Paris Diderot).

 

Theme 3. Chirality and Natural Products. Acquisition of a VCD spectrometer (Jasco apparatus) for 2018 (Funding: Région Ile-de-France, DIM Analytics)

 

Publications___________________________________________

 

P21. E. Chirkin, F.-H. Porée Curr. Org. Chem. 2016, 20, 2284-2325. Guest Editor

P20. F. Chapeland-Leclerc, A. Dilmaghani, L. Ez-Zaki, S. Boisnard, B. Da Silva, T. Gaslonde, F.-H. Porée, G Ruprich-Robert Fungal Genet. Biol. 2015, 84, 1-11.

P19. E. Chirkin, S. Michel, F.-H. Porée J. Org. Chem. 2015, 80, 6525-6528.

P18. E. Chirkin, W. Atkatlian,Q. Do, T. Gaslonde, T.-H. Dufat, S. Michel,P. Lemoine, G. Genta-Jouve, F.-H. Porée Nat. Prod. Res. 2015.DOI 10.1080/14786419.2015.1023727.

P17. E. Chirkin, W. Atkatlian, F.-H. Porée, The Securinega Alkaloids. In The Alkaloids; Knölker, H-J., Ed.; 2015; 74, pp 1–120.

P16. D. Markovic, M. Kolympadi, B. Deguin, F.-H. Porée, M. Turks Nat. Prod. Rep. 2015, 32, 230-255. Cover Picture.

P15. M. Fomani, E. N. Happi, Kouam, F.-H Porée, M.-C. Lallemand, A. F. K. Waffo, J. D. Wansi Z. Naturforsch. B, 2015, 70, 71-75.

P14. X. Cachet, F.-H. Porée, S. Michel, P. Lemoine Acta. Cryst. 2013, E69, o1389-1390

P13. X. Cachet, F.-H. Porée RSC Adv. 2013, 3, 12466-12484.

P12. L. Donati, P. Leproux, E. Prost, S. Michel, F. Tillequin, V. Gandon, F.-H. Porée Chem. Eur. J. 2011, 17, 12809-12819.

P11. C. Genès, G. Lenglet, S. Depauw, R. Nhili, S. Prado, M.-H. David-Cordonnier, S. Michel, F. Tillequin, F.-H. Porée Eur J. Med. Chem. 2011, 46, 2117-2131.

P10. L. Donati, S. Michel, F. Tillequin, F.-H. Porée Org. Lett. 2010, 12, 156-158.

P9. T. Serbetçi, C. Genès, S. Depauw, S. Prado, F.-H. Porée, M.-P. Hildebrand, M.-H. David-Cordonnier, S. Michel, F. Tillequin Eur J. Med. Chem. 2010, 45, 2547-2558.

P8. C. Genès, S. Michel, F. Tillequin, F.-H. Porée Tetrahedron 2009, 65, 10009-10015.

P7. Fürstner, L. C. Bouchez, L. Morency, J.-A. Funel, V. Liepnis, F.-H. Porée, R. Gilmour, D. Laurich, F. Beaufils, M. Tamiya Chem. Eur. J. 2009, 15, 3983-4010.

P6. E. de Lemos, F.-H. Porée, A. Bourin, J. Barbion, E. Agouridas, M.-I. Lannou, A. Commerçon, J.-F. Betzer, A. Pancrazi, J. Ardisson Chem. Eur. J. 2008, 14, 11092-11112.

P5. E.de Lemos, F.-H. Porée, A. Commerçon, J.-F. Betzer, A. Pancrazi, J. Ardisson Angew. Chem. Int. Ed. 2007, 46, 1917-1921.

P4. A. Fürstner, L. C. Bouchez, J.-A. Funel, V. Liepnis, F.-H. Porée, R. Gilmour, F. Beaufils, D. Laurich, M. Tamiya Angew. Chem. Int. Ed. 2007, 46, 9265-9270.

P3. S. Centonze-Audureau, F.-H. Porée, J.-F. Betzer, J.-D. Brion, A. Pancrazi, J. Ardisson Synlett 2005, 981-985.

P2. F.-H. Porée, J. Barbion, S. Dhulut, J.-F. Betzer, A. Pancrazi, J. Ardisson Synthesis 2004, 3017-3022.

P1. F.-H. Porée, A. Clavel, J.-F. Betzer, A. Pancrazi, J. Ardisson Tetrahedron Lett. 2003, 44, 7553-7556.

 

F.-H. Porée, S. Michel, F.Tillequin Revue du Palais de la Découverte 2009, 364, 42-59.

 

Extras________________________________________________

Marathon de Paris (2002, 2005, 2007, 2009, 2014, 2016), 20 km de Paris (2012, 2016), Paris Versailles (2017)

 

Contact_______________________________________________

François-Hugues Porée

PharmD, PhD in Chemistry

Assistant Professor

Laboratoire de Pharmacognosie UMR CNRS 8638

Faculté de Pharmacie – Université Paris Descartes

4 avenue de l’Observatoire

F-75006 Paris, FRANCE

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