François-Hugues Porée, Assistant Professor (MC-HDR)

 Vitae______________________________________________

 2019. Head of the teaching unit Pharmacognosy-Botany-Mycology

2012. HDR (habilitation). Université Paris Descartes

2005. Assistant Professor (Laboratoire de Pharmacognosie UMR CNRS 8638, Faculté de Pharmacie de Paris - Université Paris Descartes)

2003-2004. Postdoctoral fellow at the Max Planck Institut für Kohlenforschung (Pr Fürstner)

2003. PhD in Organic Chemistry at Université de Cergy-Pontoise (Dr Pancrazi and Pr Ardisson) (Dina Surdin Award from the French Chemical Society)

2001. PhD in Pharmacy. Faculté de Pharmacie de Châtenay-Malabry, Université Paris Sud

2000. Master Degree in Organic Chemistry (Ecole Polytechnique, Palaiseau, France)

1976. Born in Paris (France)

 

Research_____________________________________________

Keywords. Alkaloids, total synthesis, catalysis, chirality, mushrooms,

Theme 1. Synthesis of Natural Product Analogs for SAR studies: (1) Securinega alkaloids series. (2) Morphinan series

 

Theme 2. Phytochemical investigations. (1) Phytochemical studies on plants belonging to the Phyllanthaceae family. (2) Connecting genetics to secondary metabolites: phytochemical studies on selected filamentous fungi (collaboration with Dr F Leclerc, G Ruprich-Robert and H Lalucque, Université Paris Diderot).

 

Theme 3. Chirality and Natural Products. Acquisition of a VCD spectrometer (Jasco apparatus) for 2018 (Funding: Région Ile-de-France, DIM Analytics)

 

Publications___________________________________________

 

P24. L. Shen, F.-H. Porée, T. Gaslonde, H. Lalucque, F. Chapeland-Leclerc, G. Ruprich-Robert Environmental Microbiology, 2019, DOI 10.1111/1462-2920.14698.

P23. E. Chirkin, C. Bouzidi, F.-H. Porée Synthesis 2019, DOI 10.1055/s-0037-1612063.

P22. P. Menelle, K. Cottet, Y. Fromentin, T. Gaslonde, F.-H. Porée, D. Buisson, M.-C. Lallemand Tetrahedron Lett. 2017, 58, 4876-4879. DOI 10.1016/j.tetlet.2017.11.041.

P21. E. Chirkin, F.-H. Porée Curr. Org. Chem. 2016, 20, 2284-2325. Guest Editor

P20. F. Chapeland-Leclerc, A. Dilmaghani, L. Ez-Zaki, S. Boisnard, B. Da Silva, T. Gaslonde, F.-H. Porée, G Ruprich-Robert Fungal Genet. Biol. 2015, 84, 1-11.

P19. E. Chirkin, S. Michel, F.-H. Porée J. Org. Chem. 2015, 80, 6525-6528.

P18. E. Chirkin, W. Atkatlian,Q. Do, T. Gaslonde, T.-H. Dufat, S. Michel,P. Lemoine, G. Genta-Jouve, F.-H. Porée Nat. Prod. Res. 2015.DOI 10.1080/14786419.2015.1023727.

P17. E. Chirkin, W. Atkatlian, F.-H. Porée, The Securinega Alkaloids. In The Alkaloids; Knölker, H-J., Ed.; 2015; 74, pp 1–120.

P16. D. Markovic, M. Kolympadi, B. Deguin, F.-H. Porée, M. Turks Nat. Prod. Rep. 2015, 32, 230-255. Cover Picture.

P15. M. Fomani, E. N. Happi, Kouam, F.-H Porée, M.-C. Lallemand, A. F. K. Waffo, J. D. Wansi Z. Naturforsch. B, 2015, 70, 71-75.

P14. X. Cachet, F.-H. Porée, S. Michel, P. Lemoine Acta. Cryst. 2013, E69, o1389-1390

P13. X. Cachet, F.-H. Porée RSC Adv. 2013, 3, 12466-12484.

P12. L. Donati, P. Leproux, E. Prost, S. Michel, F. Tillequin, V. Gandon, F.-H. Porée Chem. Eur. J. 2011, 17, 12809-12819.

P11. C. Genès, G. Lenglet, S. Depauw, R. Nhili, S. Prado, M.-H. David-Cordonnier, S. Michel, F. Tillequin, F.-H. Porée Eur J. Med. Chem. 2011, 46, 2117-2131.

P10. L. Donati, S. Michel, F. Tillequin, F.-H. Porée Org. Lett. 2010, 12, 156-158.

P9. T. Serbetçi, C. Genès, S. Depauw, S. Prado, F.-H. Porée, M.-P. Hildebrand, M.-H. David-Cordonnier, S. Michel, F. Tillequin Eur J. Med. Chem. 2010, 45, 2547-2558.

P8. C. Genès, S. Michel, F. Tillequin, F.-H. Porée Tetrahedron 2009, 65, 10009-10015.

P7. Fürstner, L. C. Bouchez, L. Morency, J.-A. Funel, V. Liepnis, F.-H. Porée, R. Gilmour, D. Laurich, F. Beaufils, M. Tamiya Chem. Eur. J. 2009, 15, 3983-4010.

P6. E. de Lemos, F.-H. Porée, A. Bourin, J. Barbion, E. Agouridas, M.-I. Lannou, A. Commerçon, J.-F. Betzer, A. Pancrazi, J. Ardisson Chem. Eur. J. 2008, 14, 11092-11112.

P5. E.de Lemos, F.-H. Porée, A. Commerçon, J.-F. Betzer, A. Pancrazi, J. Ardisson Angew. Chem. Int. Ed. 2007, 46, 1917-1921.

P4. A. Fürstner, L. C. Bouchez, J.-A. Funel, V. Liepnis, F.-H. Porée, R. Gilmour, F. Beaufils, D. Laurich, M. Tamiya Angew. Chem. Int. Ed. 2007, 46, 9265-9270.

P3. S. Centonze-Audureau, F.-H. Porée, J.-F. Betzer, J.-D. Brion, A. Pancrazi, J. Ardisson Synlett 2005, 981-985.

P2. F.-H. Porée, J. Barbion, S. Dhulut, J.-F. Betzer, A. Pancrazi, J. Ardisson Synthesis 2004, 3017-3022.

P1. F.-H. Porée, A. Clavel, J.-F. Betzer, A. Pancrazi, J. Ardisson Tetrahedron Lett. 2003, 44, 7553-7556.

 

F.-H. Porée, S. Michel, F.Tillequin Revue du Palais de la Découverte 2009, 364, 42-59.

 

Extras________________________________________________

Marathon de Paris (2002, 2005, 2007, 2009, 2014, 2016), 20 km de Paris (2012, 2016), Paris Versailles (2017), Ruée des Fadas (2018), Spartan Race Super (2018)

 

Contact_______________________________________________

François-Hugues Porée

PharmD, PhD in Chemistry

Assistant Professor HDR

Laboratoire de Pharmacognosie UMR CNRS CiTCOM 8036

Faculté de Pharmacie – Université Paris Descartes

4 avenue de l’Observatoire

F-75006 Paris, FRANCE

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