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Bienvenue sur le site de l'équipe de Pharmacognosie,
Produits Naturel, Analyse et Synthese
UMR 8038 CNRS-Université PARIS DESCARTES
Publication 2019
Severity of manchineel fruit (Hippomane mancinella) poisoning: a retrospective case series of 97 patients from French Poison Control Centers, Toxicon, Available online 28 February 2019,
In Press, Accepted Manuscript.
Denis Boucaud-Maitre, Xavier Cachet, Chouaha Bouzidi, Ludivine Riffault-Valois,Caroline Dupuy, Robert Garnier, Jérôme Langrand,
Publication 2018
Clerodane furanoditerpenoids as the probable cause of toxic hepatitis induced by Tinospora crispa
Xavier Cachet, Jerôme Langrand, Ludivine Riffault-Valois, Chouaha Bouzidi, Cyril Colas, Annabelle Dugay, Sylvie Michel & Denis Boucaud-Maitre
Scientific Reportsvolume 8, Article number: 13520 (2018)
Publication 2017
Antiscalant properties of Herniaria glabra aqueous solution,
Hermer O., Cheap-Charpentier H., Cachet X., Perrot H., Lédion J., Gélus D.,Pécoul N. Litaudon M., Roussi F.,
Desalination 409 (2017) 157-162.
Publications 2016
Catalytic oxidative coupling of primary amines under air: A flexible route to benzimidazole derivatives.
Nguyen K.M.H.; Largeron, M.
Eur. J. Org. Chem., 2016, DOI:10.1002/ejoc.201501520
Detection of aristolochic acids I and II in "Chiniy-trèf", a traditional medicinal
preparation containing caterpillars feeding on Aristolochia trilobata L. in Martinique,
French West Indies.
Cachet X., Langrand J., Bottai C., Dufat H., Locatelli-Jouans C., Nossin E.,
Boucaud-Maitre D.,
Toxicon, 2016, in press, accepted manuscript.
Publications 2015
"Symphonia globulifera, a widespread source of complex metabolites with potent biological activities" Y.
Fromentin, K. Cottet, M. Kritsanida, S. Michel, N. Gaboriaud-Kolar, M.-C. Lallemand, Planta Med., 2015, 81, 95-107.
"Isolation of Guttiferones from Renewable Parts of Symphonia globulifera by Centrifugal Partition Chromatography"
K. Cottet, Y. Fromentin, M. Kritsanida, R. Grougnet, G. Odonne, C. Duplais, S. Michel, M.-C. Lallemand
Planta Med., 2015, 81, 1-5.
Cymoside, a monoterpene indole alkaloid with a hexacyclic fused skeleton from Chimarrhis cymosa
Christelle Lémus,Marina Kritsanida, Alban Canet, Grégory Genta-Jouve, SylvieMichel, Brigitte Deguin,
Raphaël Grougnet
Tetrahedron Letters 2015, 56 (40), 5377-5380
Viability of a [2+2+1] Hetero-Pauson-Khand Cycloaddition Strategy toward
Securinega Alkaloids: Synthesis of the BCD-Ring Core of Securinine and Related Alkaloids
Egor Chirkin, Sylvie Michel and François-Hugues Porée
J. Org. Chem. 2015, doi: 10.1021/acs.joc.5b011118
Chiroptical study and absolute configuration of securinine oxidation products
Egor Chirkin, William Atkatlian, Quyên Do, Thomas Gaslonde, Thi-Hanh Dufat, Sylvie Michel, Pascale Lemoine, Grégory Genta-Jouve & François-Hugues Porée.
Natural Product Research 2015, 10.1080/14786419.2015.1023727
A prenylated acridone alkaloid and ferulate xanthone from barks of Citrus medica (Rutaceae)
Book Chapter:
E. Chirkin, W. Atkatlian, F.-H. Porée, The Securinega Alkaloids.
In The Alkaloids; Knölker, H-J., Ed.; 2015; pp 1–120.
COVER PICTURE: The isolation and synthesis of neodolastane diterpenoids
Markovic, D.; Kolympadi, M.; Deguin, B.; Porée, F.-H.; Turks, M. Nat. Prod. Rep. 2015, 32, 230-255.
A Bioinspired catalytic aerobic oxidative C-H functionalization of primary aliphatic amines: synthesis of 1,2-disubstituted benzimidazoles.
Nguyen, K.M.H. Largeron, Martine.
Chem. Eur. J., 2015, 21, 12606-12610 (Hot Paper).
Polycyclic Polyprenylated Xanthones from Symphonia globulifera: Isolation and Biomimetic Electrosynthesis.
Cottet, K.; Neudörffer, A.; Kritsanida, M. ; Michel, S. ; Lallemand, M.-C. ; Largeron, M.
J. Nat. Prod., 2015, 78, 2136-2140.
Regiospecific synthesis of neuroprotective 1,4-benzoxazine derivatives through a tandem oxidation-Diels-Alder reaction.
Nguyen, K.M.H. Schwendimann, L. Gressens, P. Largeron, M.
Org. Biomol. Chem. 2015, 13, 3749-3756.
A metalloenzyme-like catalytic system for the chemoselective oxidative cross-coupling of primary amines to imines under ambient conditions.
Martine Largeron, M. Fleury, M.-B.
Chem. Eur. J., 2015, 21, 3815-3820.
Horizon 2020
Call: H2020-MSCA-RISE-2015
Topic: MSCA-RISE-2015
Action: MSCA-RISE
Début du projet : mars 2016
Durée : 4 ans
Le Laboratoire de Pharmacognosie (Pr S. Michel Responsable scientifique, Dr Marina Kritsanida, Dr Sabrina Boutefnouchet, Dr Raphaël Grougnet) participe au projet européen EXANDAS : “Exploitation of aromatic plants’ by-products for the development of novel cosmeceuticals and food supplements” (MSCA-RISE-2015, Grant Agreement No 691247) qui réunit 6 Institutions académiques et 6 PME de 7 pays d’Europe et d’Afrique du Nord (Grèce, France, Allemagne, Bulgarie, Maroc, Algérie, Tunisie).
Link: https://www.exandas-project.eu/